BDBM468725 US10807959, Example 137

SMILES Cc1ccnc(c1)C(NC(=O)c1cc(Cn2ccnc2)cc(c1)-c1ccc(F)nc1C)C1CC1

InChI Key InChIKey=UBPIMOHMVJQFFW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 468725   

TargetWD repeat-containing protein 5(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 468725BDBM468725(US10807959, Example 137)
Affinity DataKi: <1nMAssay Description:FPA Assay protocol adopted from Karatas et al. (J. Med. Chem. 2010, 5179.; J. Amer. Chem. Soc. 2013, 669.): WDR5 (Δ23, residues 24-334), is expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetWD repeat-containing protein 5(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 468725BDBM468725(US10807959, Example 137)
Affinity DataKi:  2nMAssay Description:A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent