BDBM468952 US10807959, Example C27

SMILES COc1cc(CNC(=O)c2cc(CNC3=NCCC3)cc(n2)-c2ccc(F)cc2C(F)(F)F)cc(OC)c1

InChI Key InChIKey=RCVOAEXGASLDFS-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 468952   

TargetWD repeat-containing protein 5(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 468952BDBM468952(US10807959, Example C27)
Affinity DataKi:  1.58nMAssay Description:FPA Assay protocol adopted from Karatas et al. (J. Med. Chem. 2010, 5179.; J. Amer. Chem. Soc. 2013, 669.): WDR5 (Δ23, residues 24-334), is expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent