BDBM468982 US10807974, Example 1::US10995088, Example 1::US11608330, Example 1

SMILES NCc1ccc(s1)S(=O)(=O)Cc1ccccc1

InChI Key InChIKey=RQFDYTYGIXKANU-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 468982   

TargetProtein-lysine 6-oxidase(Pig)
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM468982(US10807974, Example 1 | US10995088, Example 1 | US...)
Affinity DataIC50: 2.70E+3nMAssay Description:LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetLysyl oxidase homolog 2(Human)
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM468982(US10807974, Example 1 | US10995088, Example 1 | US...)
Affinity DataIC50: 2.20E+3nMAssay Description:LOXL2 batch is obtained from R&D systems/Bio-techne. Incubate for 20 min at room temp on a plate shaker.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetLysyl oxidase homolog 2(Human)
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM468982(US10807974, Example 1 | US10995088, Example 1 | US...)
Affinity DataIC50: 2.40E+3nMAssay Description:LOXL2 batch is obtained from R&D systems/Bio-techne. Incubate for 20 hours at room temp on a plate shaker.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetProtein-lysine 6-oxidase(Human)
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM468982(US10807974, Example 1 | US10995088, Example 1 | US...)
Affinity DataIC50: 2.70E+3nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

TargetLysyl oxidase homolog 2(Human)
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM468982(US10807974, Example 1 | US10995088, Example 1 | US...)
Affinity DataIC50: 2.20E+3nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

TargetLysyl oxidase homolog 2(Human)
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM468982(US10807974, Example 1 | US10995088, Example 1 | US...)
Affinity DataIC50: 2.40E+3nMAssay Description:10. Incubate for 20 hrs at room temp on a plate shaker, protected from light.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Pig)
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM468982(US10807974, Example 1 | US10995088, Example 1 | US...)
Affinity DataIC50: 2.70E+3nMAssay Description:LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.Assay Plates:Black, flat bottom 96 well platesProcedure:1. Dilute LOX en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

TargetLysyl oxidase homolog 2(Human)
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM468982(US10807974, Example 1 | US10995088, Example 1 | US...)
Affinity DataIC50: 2.20E+3nMAssay Description:LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.Assay Plates:Black, flat bottom 96 well platesProcedure:1. Dilute LOX en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

TargetLysyl oxidase homolog 2(Human)
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM468982(US10807974, Example 1 | US10995088, Example 1 | US...)
Affinity DataIC50: 2.40E+3nMAssay Description:MAO-Glo Assay Kit: Promega, Cat No. V1402MAO-A Enzyme: Promega, Cat No. V1452Clorgyline: Sigma, Cat No. M3778 (50 mg)Assay Plates:96 well white polys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent