BDBM473886 US10858316, Compound LC-4-141::acetoxymethyl 2- hydroxy-4- (N-isobutyl- 4- phenoxyphenyl- sulfonamido) benzoate

SMILES CC(C)CN(c1ccc(C(=O)OCOC(C)=O)c(O)c1)S(=O)(=O)c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=HGSCFHSKKDLOKB-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 473886   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland, Baltimore

US Patent
LigandPNGBDBM473886(acetoxymethyl 2- hydroxy-4- (N-isobutyl- 4- phenox...)
Affinity DataKi: >5.00E+5nMAssay Description:Molecular modeling and SILCS functional group affinity mapping (FragMaps) of the Mcl-1 binding site indicated that the carboxylic acid of designed mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent