BDBM476337 US10874687, Compound 1A

SMILES CNc1nc(N)nc2n(cnc12)[C@@H]1O[C@H](CO[P@@](=O)(N[C@@H](C)C(=O)OC(C)C)Oc2ccccc2)[C@@H](O)[C@@]1(C)F

InChI Key InChIKey=OISLSHLAXHALQZ-LZEIJKKFSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 476337   

TargetReplicase polyprotein 1ab(HCoV-229E)
Atea Pharmaceuticals

US Patent
LigandPNGBDBM476337(US10874687, Compound 1A)
Affinity DataEC50:  1.60E+3nMAssay Description:Compound activity against coronavirus was based on inhibition of virus induced cytopathogenicity acutely infected with a multiplicity of infection (m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-OC43)
Atea Pharmaceuticals

US Patent
LigandPNGBDBM476337(US10874687, Compound 1A)
Affinity DataEC50:  2.00E+3nMAssay Description:Compound activity against coronavirus was based on inhibition of virus induced cytopathogenicity acutely infected with a multiplicity of infection (m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-OC43)
Atea Pharmaceuticals

US Patent
LigandPNGBDBM476337(US10874687, Compound 1A)
Affinity DataEC50:  1.60E+3nMAssay Description:Compound activity against coronavirus was based on inhibition of virus induced cytopathogenicity acutely infected with a multiplicity of infection (m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)
Atea Pharmaceuticals

US Patent
LigandPNGBDBM476337(US10874687, Compound 1A)
Affinity DataEC50:  2.00E+3nMAssay Description:Compound activity against coronavirus was based on inhibition of virus induced cytopathogenicity acutely infected with a multiplicity of infection (m...More data for this Ligand-Target Pair
In DepthDetails US Patent