BDBM477526 US10889555, Example 298::US11634395, Example 298

SMILES COc1ccc(cc1)-c1ccc(F)c([C@@H](C)[C@H](NS(=O)(=O)c2ccc(Cl)cc2OC)c2n[nH]c(=O)o2)c1C

InChI Key InChIKey=UFCZLLHJHLQHLW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 477526   

TargetMuscarinic acetylcholine receptor M1/M2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM477526(US10889555, Example 298 | US11634395, Example 298)
Affinity DataIC50: 300nMAssay Description:First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent

TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Human)
Taiho Pharmaceutial

US Patent
LigandPNGBDBM477526(US10889555, Example 298 | US11634395, Example 298)
Affinity DataIC50: 300nMAssay Description:The inhibitory activity against the ribonucleotide reduction reaction (hereinafter referred to as RNR reaction) of the test compound was determined b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent