BDBM479206 US10894789, Compound 93

SMILES C[C@@H]1CC(F)(F)CN(C1CNc1ncc(cn1)C(F)(F)F)C(=O)c1cn(C)nc1-c1ccccn1

InChI Key InChIKey=HXQOUXCCTGZNOX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 479206   

TargetOrexin/Hypocretin receptor type 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM479206(US10894789, Compound 93)
Affinity DataIC50: 156nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO OX1 or CHO OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
Go to US Patent

TargetOrexin receptor type 2(Human)
Astrazeneca

US Patent
LigandPNGBDBM479206(US10894789, Compound 93)
Affinity DataIC50: 5.00E+3nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO OX1 or CHO OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
Go to US Patent