BDBM479245 US10894789, Compound 100

SMILES COc1nc(NCC2[C@@H](C)CC(F)(F)CN2C(=O)c2nn(C)cc2-c2ccccn2)ncc1C(F)(F)F

InChI Key InChIKey=SLTQWNJXAADIJL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 479245   

TargetOrexin/Hypocretin receptor type 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM479245(US10894789, Compound 100)
Affinity DataIC50: 9nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO OX1 or CHO OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
Astrazeneca

US Patent
LigandPNGBDBM479245(US10894789, Compound 100)
Affinity DataIC50: 5.00E+3nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO OX1 or CHO OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent