BDBM479473 ML300-based SC inhibitor 12

SMILES CS(=O)(=O)Nc1ccc(cc1)N(Cc1ccsc1)C(=O)Cn1nnc2ccccc12

InChI Key InChIKey=PAOYPYMKBNVXRO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 479473   

TargetReplicase polyprotein 1ab(2019-nCoV)
Cleveland Clinic

LigandPNGBDBM479473(ML300-based SC inhibitor 12)
Affinity DataIC50:  1.61E+3nMAssay Description:The protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, end point assay adapted from a previ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
Cleveland Clinic

LigandPNGBDBM479473(ML300-based SC inhibitor 12)
Affinity DataIC50:  1.40E+3nMAssay Description:The protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, end point assay adapted from a previ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed