BDBM480247 US10899738, Cpd. No 308::rac-(1S,2R)-2-(cyano(1-(3- (4- cyanophenoxy)propyl) piperidin-4-yl)(2- fluorophenyl)methyl)cyclopentyl acetate

SMILES CC(=O)O[C@H]1CCC[C@@H]1C(C#N)(C1CCN(CCCOc2ccc(cc2)C#N)CC1)c1ccccc1F

InChI Key InChIKey=CJQQTVQISYHBBS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480247   

TargetMenin(Human)
University of Michigan

US Patent
LigandPNGBDBM480247(rac-(1S,2R)-2-(cyano(1-(3- (4- cyanophenoxy)propyl...)
Affinity DataIC50: 66nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
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