BDBM480560 US10899769, Example 44a

SMILES C[C@@H]1C(=O)N(C)Cc2c(-c3cccc4cc(-c5noc(=O)[nH]5)ncc34)nc(C3CC3)n21

InChI Key InChIKey=VAHCMBWTAVBSJY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 480560   

TargetBromodomain-containing protein 4 [49-170](Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 480560BDBM480560(US10899769, Example 44a)
Affinity DataIC50: 68nMAssay Description:BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
US Patent

TargetCREB-binding protein [1081-1197](Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 480560BDBM480560(US10899769, Example 44a)
Affinity DataIC50: 2.50E+4nMAssay Description:CBP: 5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
US Patent