BDBM480918 US10906888, Example 132

SMILES O=C(N1CCC2(C1)CCOCC2)c1cnc(NC2(COC2)c2cnccn2)nc1

InChI Key InChIKey=ULWCEJKZARPREP-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 480918   

TargetPantetheinase(Human)
Pfizer

US Patent

LigandBDBM480918(US10906888, Example 132)Copy SMILESCopy InChI

Affinity DataIC50: 0.349nMAssay Description:The test inhibitors were solubilized in DMSO to a stock concentration of 30 mM. On the day of the assay, dose response plates were prepared by diluti...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/22/2021
Entry Details
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TargetPantetheinase(Human)
Pfizer

US Patent

LigandBDBM480918(US10906888, Example 132)Copy SMILESCopy InChI

Affinity DataIC50: 0.350nMAssay Description:Inhibition of recombinant N-terminal FLAG/His6-tagged human vanin-1 expressed in CHO cells using Pantetheine-7-amino-4-trifluoromethykournarin as sub...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/7/2023
Entry Details Article
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