BDBM483149 US10919885, Compound No. 298

SMILES O=C(N1CCC(CC1)Oc1ccccc1)c1cc(on1)-c1ccc2OCOc2c1

InChI Key InChIKey=FUIDQGZBUBUWMJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483149   

TargetStearoyl-CoA desaturase 5(Human)
Yumanity Therapeutics

US Patent
LigandPNGBDBM483149(US10919885, Compound No. 298)
Affinity DataIC50: 2.92E+3nMAssay Description:Strains expressing SCD1 or SCD5 as the sole desaturase, the human SCD1 and SCD5 genes were used to evaluate inhibition of SCD1/SCD5 using reduced gro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Yumanity Therapeutics

US Patent
LigandPNGBDBM483149(US10919885, Compound No. 298)
Affinity DataIC50: 6.22E+3nMAssay Description:Strains expressing SCD1 or SCD5 as the sole desaturase, the human SCD1 and SCD5 genes were used to evaluate inhibition of SCD1/SCD5 using reduced gro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent