BDBM483329 US10919895, Compound Ib-01

SMILES CCCCNCc1ccc(Cn2c(O)nc3c(N)nc(OCCCC)nc23)nc1

InChI Key InChIKey=YHEVTZTZXHJQJW-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483329   

TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM483329(US10919895, Compound Ib-01)
Affinity DataEC50:  15nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetInterleukin-6(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM483329(US10919895, Compound Ib-01)
Affinity DataEC50:  77nMAssay Description:Compounds diluted in DMSO were transferred to individual wells of a Matrix Technologies clear, V-bottom 384-well plate using ECHO acoustic liquid han...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent