BDBM483818 4-chloro-1-(trans-5- ((2-methyl-3- (trifluoromethyl)- benzyl)oxy)- octahydrocyclopenta- [c]pyrrole- 2-carbonyl)-1H- pyrazole-3- carboxylic acid::US10927105, Ex 341::US11655217, Example 341

SMILES Cc1c(CO[C@@H]2C[C@H]3CN(C[C@H]3C2)C(=O)n2cc(Cl)c(n2)C(O)=O)cccc1C(F)(F)F

InChI Key InChIKey=GEYAGMWILIMNJW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483818   

TargetMonoglyceride lipase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483818(US10927105, Ex 341 | 4-chloro-1-(trans-5- ((2-meth...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483818(US10927105, Ex 341 | 4-chloro-1-(trans-5- ((2-meth...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
US Patent