BDBM483856 1,1,1,3,3,3- hexafluoropropan-2- yl 4-(7-cyclobutyl- N-methyl-5,6,7,8- tetrahydroimidazo- [l,2-a]pyrazine- 2-carboxamido)-4- methylpiperidine-1- carboxylate::US10927105, Ex 398::US11655217, Example 398

SMILES CN(Cc1ccc(cc1N1CCCC1)C(F)(F)F)C1(C)CCN(CC1)C(=O)n1cc(C)c(n1)C(O)=O

InChI Key InChIKey=UOCBXQRMDNLBJL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483856   

TargetMonoglyceride lipase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483856(US10927105, Ex 398 | 1,1,1,3,3,3- hexafluoropropan...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483856(US10927105, Ex 398 | 1,1,1,3,3,3- hexafluoropropan...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
US Patent