BDBM484192 4-isopropyl-2,2-dimethyl-9- phenethyl-1-oxa-4,9- diazaspiro[5.5]undecane::US10927128, Example 113::US11649248, Example 113

SMILES CC(C)N1CC(C)(C)OC2(CCN(CCc3ccccc3)CC2)C1

InChI Key InChIKey=ZAZIQRKOJQJBFK-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 484192   

TargetAP-4 complex subunit sigma-1(Human)
Esteve Pharmaceuticals.

US Patent
LigandPNGBDBM484192(4-isopropyl-2,2-dimethyl-9- phenethyl-1-oxa-4,9- d...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484192(4-isopropyl-2,2-dimethyl-9- phenethyl-1-oxa-4,9- d...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent