BDBM484333 (S)-l-(2-(1-(4-((3,4- difluorophenoxy) methyl)phenyl)imidazo [1,5-a]pyrazin-3-yl) pyrrolidin-1-yl)but- 2-yn-1-one::US10933063, Compound 132::US11554118, Compound 132

SMILES CC#CC(=O)N1CCC[C@H]1c1nc(-c2ccc(COc3ccc(F)c(F)c3)cc2)c2cnccn12

InChI Key InChIKey=KGSQFIHUZLQRRG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 484333   

TargetTyrosine-protein kinase BTK(Human)
Suzhou Baijibugong Pharmaceutical Technology

US Patent
LigandPNGBDBM484333((S)-l-(2-(1-(4-((3,4- difluorophenoxy) methyl)phen...)
Affinity DataIC50: 5.50E+3nMAssay Description:Btk and Other Kinases: Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were perform...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Suzhou Baijibugong Pharmaceutical Technology

US Patent
LigandPNGBDBM484333((S)-l-(2-(1-(4-((3,4- difluorophenoxy) methyl)phen...)
Affinity DataIC50: 5.50E+3nMAssay Description:Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were performed in a reaction volume...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details Article
US Patent