BDBM484700 US10934297, Compound 93::US11713320, Compound 93

SMILES O=C(Nc1ccc(nc1)N1CCCC1)c1n[nH]c2ccc(cc12)-c1cnn(c1)C1CCNCC1

InChI Key InChIKey=UCEAFPMVTVBPCI-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 484700   

LigandPNGBDBM484700(US10934297, Compound 93 | US11713320, Compound 93)
Affinity DataEC50:  6nMAssay Description:DYRK1A: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
Go to US Patent

LigandPNGBDBM484700(US10934297, Compound 93 | US11713320, Compound 93)
Affinity DataEC50:  6nMAssay Description:Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response curves ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Samumed

US Patent
LigandPNGBDBM484700(US10934297, Compound 93 | US11713320, Compound 93)
Affinity DataEC50:  430nMAssay Description:GSK3β: Each compound is dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-respo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Samumed

US Patent
LigandPNGBDBM484700(US10934297, Compound 93 | US11713320, Compound 93)
Affinity DataEC50:  430nMAssay Description:Each compound is dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response curves f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
Go to US Patent