BDBM484707 US10934297, Compound 100::US11713320, Compound 100

SMILES CC(C)CN1CC[C@H](NC(=O)c2n[nH]c3ccc(cc23)-c2cnc(C)n2C)[C@@H](F)C1

InChI Key InChIKey=VTZUYAKVRFHVFE-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 484707   

TargetGlycogen synthase kinase-3 beta(Human)
Samumed

US Patent
LigandPNGBDBM484707(US10934297, Compound 100 | US11713320, Compound 10...)
Affinity DataEC50:  43nMAssay Description:GSK3β: Each compound is dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-respo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Samumed

US Patent
LigandPNGBDBM484707(US10934297, Compound 100 | US11713320, Compound 10...)
Affinity DataEC50:  43nMAssay Description:Each compound is dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response curves f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent

LigandPNGBDBM484707(US10934297, Compound 100 | US11713320, Compound 10...)
Affinity DataEC50:  46nMAssay Description:DYRK1A: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
US Patent

LigandPNGBDBM484707(US10934297, Compound 100 | US11713320, Compound 10...)
Affinity DataEC50:  46nMAssay Description:Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response curves ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
US Patent