BDBM486416 3-(3-cyclopropylphenyl)-N-(1,1- dioxidotetrahydrothiophen-3-yl)- 1-(4-fluorophenyl)-1H-indole-6- carboxamide (racemic)::US10947222, Example 46

SMILES Fc1ccc(cc1)-n1cc(-c2cccc(c2)C2CC2)c2ccc(cc12)C(=O)NC1CCS(=O)(=O)C1

InChI Key InChIKey=VHQNWZCNGIIOEN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 486416   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM486416(3-(3-cyclopropylphenyl)-N-(1,1- dioxidotetrahydrot...)
Affinity DataIC50:  2.10nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent