BDBM486563 US10947251, Example 35
SMILES [H][C@]12CCC(=O)N(c3cc(F)c(cc3OC)-c3cccc(c3)C(F)(F)F)[C@]1([H])CCN(C2)S(=O)(=O)Nc1ccon1
InChI Key InChIKey=HITXLUTUQDNCFV-OXQOHEQNSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 486563
Affinity DataIC50: 2.88nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Affinity DataIC50: 49.3nMAssay Description:Heterologously Express hNav1.7 and the β1 SubunitPreparation of membranes containing recombinantly expressed sodium channels: Frozen recombinant...More data for this Ligand-Target Pair