BDBM488208 2-(5-(cyclopropylmethyl)- 4-(3-fluoro-4-sulfamoylbenzyl)- 3-(3-((5-methylthiophen-2- yl)ethynyl)phenyl)-1H-pyrazol-1- yl)thiazole-4-carboxamide. 1H NMR (d6-DMSO) 948; 8.12 (s, 1H), 7.72-7.44 (m, 5H), 7.62 (s, 2H), 7.24 (d, 1H, J = 4 Hz), 7.16 (d, 1H, J = 12 Hz), 7.06 (d, 1H, J = 8 Hz), 6.83 (d, 1H, J = 2 Hz), 4.18 (s, 2H), 3.16 (m, 2H), 2.5 (s, 3H), 1.08 (m, 1H), 0.34 (m, 2H), 0.17 (m, 2H); MS (ES) m/z 632.2 [M + H]+;::US10954228, Compound 163::US10954228, Compound 180
SMILES Cc1ccc(s1)C#Cc1cccc(c1)-c1nn(c(CC2CC2)c1Cc1ccc(c(F)c1)[SH+](N)=O)-c1nc(cs1)C(N)=O
InChI Key InChIKey=RRJMOECWUQCXLJ-UHFFFAOYSA-O
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 488208
Affinity DataIC50: 2.90E+4nMAssay Description:Test compounds were placed in a Greiner Bio-One (Monroe, N.C.) 1536-well black solid bottom assay plate. 200 millimolar (mM) Tris HCl, pH 7.4, 100 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+4nMAssay Description:Test compounds were placed in a Greiner Bio-One (Monroe, N.C.) 1536-well black solid bottom assay plate. 200 millimolar (mM) Tris HCl, pH 7.4, 100 mi...More data for this Ligand-Target Pair