BDBM489293 Example 1-3::US10961242, Compound 3::US11548883, Compound 3

SMILES FC(F)(F)Oc1cccc(CNc2ncc(cn2)C(=O)NCC(=O)N2CCc3[nH]nnc3C2)c1

InChI Key InChIKey=NIPNSKYNPDTRPC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 489293   

TargetAutotaxin(Human)
Legochem Biosciences

US Patent
LigandPNGBDBM489293(US10961242, Compound 3 | Example 1-3 | US11548883,...)
Affinity DataIC50: 14.3nMAssay Description:Two-fold dilution of each test compound solution (10 μM, 100% dimethyl sulfoxide) is carried out on 96-well V bottom plate (Costar 3363). After ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
Go to US Patent

TargetAutotaxin(Human)
Legochem Biosciences

US Patent
LigandPNGBDBM489293(US10961242, Compound 3 | Example 1-3 | US11548883,...)
Affinity DataIC50: 14.3nMAssay Description:Two-fold dilution of each test compound solution (10 μM, 100% dimethyl sulfoxide) is carried out on 96-well V bottom plate (Costar 3363). After ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
Go to US Patent