BDBM490291 US10968215, Compound 168::US10968215, Compound 169

SMILES COc1cc(C)[nH]c(=O)c1CNC(=O)c1cc2c(-c3cc(C)nc(C)c3)ccn2c([C@H](C)N2CCN(CC(F)(F)F)CC2)c1C

InChI Key InChIKey=PWDITNYTFWHLRG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 490291   

LigandChemical structure of BindingDB Monomer ID 490291BDBM490291(US10968215, Compound 168 | US10968215, Compound 16...)
Affinity DataIC50: 100nMAssay Description:EZH2Y641F: PRC2 complex experimental method: Experimental method: PRC2 complex (EZH2 Y641F/EED/SUZ12/RbAp48/AEBP2), H3(1-50) me1 substrate, methyl do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 490291BDBM490291(US10968215, Compound 168 | US10968215, Compound 16...)
Affinity DataIC50: 550nMAssay Description:EZH2Y641F: PRC2 complex experimental method: Experimental method: PRC2 complex (EZH2 Y641F/EED/SUZ12/RbAp48/AEBP2), H3(1-50) me1 substrate, methyl do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent