BDBM491138 4-(((3,5-Dicyano-4-ethyl-6-(4-methyl-1,4-diazepan-1-yl)pyridin-2-yl)thio)methyl)benzyl acetate::US10975056, Example 82
SMILES CCc1c(C#N)c(SCc2ccc(COC(C)=O)cc2)nc(N2CCCN(C)CC2)c1C#N
InChI Key InChIKey=XROQXIYCNDEQPJ-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 491138
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Glaxosmithkline Intellectual Property Development
US Patent
Glaxosmithkline Intellectual Property Development
US Patent
Affinity DataIC50: 660nMAssay Description:Biochemical activity of DNMT1 analyzed using SPA technology. Plates (Griener 784075) were pre-stamped with 100 nL/well of compound (11-point, 3-fold ...More data for this Ligand-Target Pair