BDBM492516 US10975084, Example 11-79::methyl 4-[6-(1- methylethyl)-7-oxo-4,7- dihydro[1,2,4]triazolo[1,5- a]pyrimidin-5-yl]benzoate

SMILES COC(=O)c1ccc(cc1)-c1[nH]c2ncnn2c(=O)c1C(C)C

InChI Key InChIKey=RPDDALQYQABVEG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492516   

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492516(US10975084, Example 11-79 | methyl 4-[6-(1- methyl...)
Affinity DataIC50: 19.4nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent