BDBM492873 N-((5-chloro-1H- indazol-3-yl)methyl)-5- (4- cyanobenzyl) nicotinamide::US10981893, Example 2

SMILES Clc1ccc2[nH]nc(CNC(=O)c3cncc(Cc4ccc(cc4)C#N)c3)c2c1

InChI Key InChIKey=RDWVZVVMYWJFGU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492873   

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandPNGBDBM492873(US10981893, Example 2 | N-((5-chloro-1H- indazol-3...)
Affinity DataIC50: 5.50E+3nMAssay Description:The ability of the compounds disclosed herein to inhibit human plasma kallikrein activity was quantified according to the procedures below.A 10 mM so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
Go to US Patent