BDBM492913 US10981905, Example 5::US11639351, Example 5

SMILES Fc1cccc(CN2CCC2)c1CNc1ccc(cn1)S(=O)(=O)Nc1cscn1

InChI Key InChIKey=WLXHPWMUYQIYRX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 492913   

TargetSodium channel protein type 8 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM492913(US10981905, Example 5 | US11639351, Example 5)
Affinity DataIC50: 8.47E+3nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
Go to US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM492913(US10981905, Example 5 | US11639351, Example 5)
Affinity DataIC50: 8.47E+3nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
Go to US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM492913(US10981905, Example 5 | US11639351, Example 5)
Affinity DataIC50: 2.65E+4nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
Go to US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM492913(US10981905, Example 5 | US11639351, Example 5)
Affinity DataIC50: 2.65E+4nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
Go to US Patent

TargetSodium channel protein type 1 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM492913(US10981905, Example 5 | US11639351, Example 5)
Affinity DataIC50: 3.00E+4nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
Go to US Patent

TargetSodium channel protein type 1 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM492913(US10981905, Example 5 | US11639351, Example 5)
Affinity DataIC50: 3.00E+4nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
Go to US Patent