BDBM498035 US11008314, Compound 119

SMILES CC(=O)Nc1ncc(Sc2cc(C(=O)N3CCN([C@@H](C3)C#N)C(=O)C=C)c(C)cc2C)s1

InChI Key InChIKey=WLWHUADWSIMVGZ-MRXNPFEDSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 498035   

TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Corvus Pharmaceuticals

US Patent
LigandPNGBDBM498035(US11008314, Compound 119)
Affinity DataIC50: <10nMAssay Description:The potency of inhibition is measured by binding affinity.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Corvus Pharmaceuticals

US Patent
LigandPNGBDBM498035(US11008314, Compound 119)
Affinity DataIC50:  55nMAssay Description:The potency of inhibition is measured by binding affinity.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Corvus Pharmaceuticals

US Patent
LigandPNGBDBM498035(US11008314, Compound 119)
Affinity DataIC50: <10nMAssay Description:The potency of inhibition is measured by binding affinity.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Corvus Pharmaceuticals

US Patent
LigandPNGBDBM498035(US11008314, Compound 119)
Affinity DataIC50: <10nMAssay Description:The potency of inhibition is measured by binding affinity.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent