BDBM498394 (1R,3S)-3-{3-[(1,3-thiazol-2- ylacetyl)amino]-1H-pyrazol-5- yl}cyclopentyl (3,3,3- trifluoropropyl)carbamate::US11014911, Example 219::US11718603, Example 219

SMILES FC(F)(F)CCNC(=O)O[C@@H]1CC[C@@H](C1)c1cc(NC(=O)Cc2nccs2)n[nH]1

InChI Key InChIKey=AWCAYVWISFXAOY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 498394   

LigandPNGBDBM498394((1R,3S)-3-{3-[(1,3-thiazol-2- ylacetyl)amino]-1H-p...)
Affinity DataKi:  3.81nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
Go to US Patent

LigandPNGBDBM498394((1R,3S)-3-{3-[(1,3-thiazol-2- ylacetyl)amino]-1H-p...)
Affinity DataKi:  3.81nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
Go to US Patent