BDBM498395 (1R,3S)-3-(3-{[(5- methylpyrazin-2- yl)acetyl]amino}-1H-pyrazol-5- yl)cyclopentyl (3,3,3- trifluoropropyl)carbamate::US11014911, Example 220::US11718603, Example 220

SMILES Cc1cnc(CC(=O)Nc2cc([nH]n2)[C@H]2CC[C@H](C2)OC(=O)NCCC(F)(F)F)cn1

InChI Key InChIKey=GCBPNULLINPOAZ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 498395   

LigandPNGBDBM498395((1R,3S)-3-(3-{[(5- methylpyrazin-2- yl)acetyl]amin...)
Affinity DataKi:  3.26nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
US Patent

LigandPNGBDBM498395((1R,3S)-3-(3-{[(5- methylpyrazin-2- yl)acetyl]amin...)
Affinity DataKi:  3.26nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent