BDBM498423 (1R,3S)-3-(3-{[(4- fluorophenyl)acetyl]amino}- 1H-pyrazol-5- yl)cyclopentyl (2,2- difluoroethyl)carbamate::US11014911, Example 248::US11718603, Example 248

SMILES FC(F)CNC(=O)O[C@@H]1CC[C@@H](C1)c1cc(NC(=O)Cc2ccc(F)cc2)n[nH]1

InChI Key InChIKey=YHOXXJKTMCVHCB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 498423   

LigandPNGBDBM498423((1R,3S)-3-(3-{[(4- fluorophenyl)acetyl]amino}- 1H...)
Affinity DataKi:  2.41nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
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LigandPNGBDBM498423((1R,3S)-3-(3-{[(4- fluorophenyl)acetyl]amino}- 1H...)
Affinity DataKi:  2.41nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
Go to US Patent