BDBM498426 (1R,3S)-3-(3-{[(2- methoxypyridin-4- yl)acetyl]amino}-1H-pyrazol- 5-yl)cyclopentyl (2,2- difluoroethyl)carbamate::US11014911, Example 251::US11718603, Example 251

SMILES COc1cc(CC(=O)Nc2cc([nH]n2)[C@H]2CC[C@H](C2)OC(=O)NCC(F)F)ccn1

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 498426   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM498426((1R,3S)-3-(3-{[(2- methoxypyridin-4- yl)acetyl]a...)
Affinity DataKi:  1.83nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM498426((1R,3S)-3-(3-{[(2- methoxypyridin-4- yl)acetyl]a...)
Affinity DataKi:  1.83nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent