BDBM498430 (1R,3S)-3-(3-{[(2- methoxypyridin-4-yl) acetyl]amino}-1H-pyrazol- 5-yl)cyclopentyl (2,2,2- trifluoroethyl)carbamate::US11014911, Example 255::US11718603, Example 255

SMILES COc1cc(CC(=O)Nc2cc([nH]n2)[C@H]2CC[C@H](C2)OC(=O)NCC(F)(F)F)ccn1

InChI Key InChIKey=ZWLJKZZKTUPAIQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 498430   

LigandPNGBDBM498430((1R,3S)-3-(3-{[(2- methoxypyridin-4-yl) acetyl]a...)
Affinity DataKi:  1.69nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
Go to US Patent

LigandPNGBDBM498430((1R,3S)-3-(3-{[(2- methoxypyridin-4-yl) acetyl]a...)
Affinity DataKi:  1.69nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
Go to US Patent