BDBM498473 (1R,3S)-3-(3-{[(5-methyl-1,3,4- oxadiazol-2-yl)acetyl]amino}- 1H-pyrazol-5-yl)cyclopentyl tert-butylcarbamate::US11014911, Example 298::US11718603, Example 298

SMILES Cc1nnc(CC(=O)Nc2cc([nH]n2)[C@H]2CC[C@H](C2)OC(=O)NC(C)(C)C)o1

InChI Key InChIKey=DBYCJDDBQKRKKC-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 498473   

LigandPNGBDBM498473((1R,3S)-3-(3-{[(5-methyl-1,3,4- oxadiazol-2-yl)ac...)
Affinity DataKi:  0.680nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

LigandPNGBDBM498473((1R,3S)-3-(3-{[(5-methyl-1,3,4- oxadiazol-2-yl)ac...)
Affinity DataKi:  0.680nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

US Patent
LigandPNGBDBM498473((1R,3S)-3-(3-{[(5-methyl-1,3,4- oxadiazol-2-yl)ac...)
Affinity DataKi:  72nMAssay Description:The purpose of GSK3β assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

US Patent
LigandPNGBDBM498473((1R,3S)-3-(3-{[(5-methyl-1,3,4- oxadiazol-2-yl)ac...)
Affinity DataKi:  72nMAssay Description:The purpose of GSK3β assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
US Patent