BDBM498516 (1R,3S)-3-(3-{[(5-methyl-1,3- thiazol-2-yl)acetyl]amino}-1H- pyrazol-5-yl)cyclopentyl (2S)- butan-2-ylcarbamate::US11014911, Example 341::US11718603, Example 341

SMILES CC[C@H](C)NC(=O)O[C@@H]1CC[C@@H](C1)c1cc(NC(=O)Cc2ncc(C)s2)n[nH]1

InChI Key InChIKey=IPERQGIPBGATIK-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 498516   

LigandPNGBDBM498516((1R,3S)-3-(3-{[(5-methyl-1,3- thiazol-2-yl)acetyl...)
Affinity DataKi:  0.640nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

LigandPNGBDBM498516((1R,3S)-3-(3-{[(5-methyl-1,3- thiazol-2-yl)acetyl...)
Affinity DataKi:  0.640nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
US Patent