BDBM498624 (1R,3S)-3-(3-{[(5- methylpyrazin-2- yl)acetyl]amino}-1H-pyrazol-5- yl)cyclopentyl (1- ethylcyclopropyl)carbamate::US11014911, Example 449::US11718603, Example 449

SMILES CCC1(CC1)NC(=O)O[C@@H]1CC[C@@H](C1)c1cc(NC(=O)Cc2cnc(C)cn2)n[nH]1

InChI Key InChIKey=PMZONLHWUYKCEE-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 498624   

LigandPNGBDBM498624((1R,3S)-3-(3-{[(5- methylpyrazin-2- yl)acetyl]am...)
Affinity DataKi:  0.390nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
Go to US Patent

LigandPNGBDBM498624((1R,3S)-3-(3-{[(5- methylpyrazin-2- yl)acetyl]am...)
Affinity DataKi:  0.390nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
Go to US Patent