BDBM498664 (1R,3S)-3-(3-{[(3$#958;)-2,3- dihydro-1-benzofuran-3- ylacetyl]amino}-1H-pyrazol-5- yl)cyclopentyl [(3$#958;)-3- methyltetrahydrofuran-3- yl]carbamate - Isomer A::US11014911, Example 489::US11014911, Example 490::US11014911, Example 491::US11014911, Example 492::US11718603, Example 492

SMILES CC1(CCOC1)NC(=O)O[C@@H]1CC[C@@H](C1)c1cc(NC(=O)CC2COc3ccccc23)n[nH]1

InChI Key InChIKey=FSFXAPFWURHBLK-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 498664   

LigandPNGBDBM498664(US11014911, Example 489 | US11014911, Example 491 ...)
Affinity DataKi:  2.39nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

LigandPNGBDBM498664(US11014911, Example 489 | US11014911, Example 491 ...)
Affinity DataKi:  2.39nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
US Patent

LigandPNGBDBM498664(US11014911, Example 489 | US11014911, Example 491 ...)
Affinity DataKi:  3.68nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

LigandPNGBDBM498664(US11014911, Example 489 | US11014911, Example 491 ...)
Affinity DataKi:  3.68nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
US Patent

LigandPNGBDBM498664(US11014911, Example 489 | US11014911, Example 491 ...)
Affinity DataKi:  3.71nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

LigandPNGBDBM498664(US11014911, Example 489 | US11014911, Example 491 ...)
Affinity DataKi:  3.71nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
US Patent

LigandPNGBDBM498664(US11014911, Example 489 | US11014911, Example 491 ...)
Affinity DataKi:  3.87nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

LigandPNGBDBM498664(US11014911, Example 489 | US11014911, Example 491 ...)
Affinity DataKi:  3.87nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
US Patent