BDBM498749 (1R,3S)-3-(3-{[(3,5- difluorophenyl)acetyl]amino}- 1H-pyrazol-5-yl)cyclopentyl (2- hydroxy-2- methylpropyl)carbamate::US11014911, Example 574::US11718603, Example 574

SMILES CC(C)(O)CNC(=O)O[C@@H]1CC[C@@H](C1)c1cc(NC(=O)Cc2cc(F)cc(F)c2)n[nH]1

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 498749   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM498749((1R,3S)-3-(3-{[(3,5- difluorophenyl)acetyl]amino}...)
Affinity DataKi:  4.07nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM498749((1R,3S)-3-(3-{[(3,5- difluorophenyl)acetyl]amino}...)
Affinity DataKi:  4.07nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent