BDBM498751 (1S,3R)-3-(3-{[(3,5- difluorophenyl)acetyl]amino}- 1H-pyrazol-5-yl)cyclopentyl [(trans-3- hydroxycyclobutyl)methyl] carbamate::US11014911, Example 576::US11718603, Example 576

SMILES O[C@H]1C[C@H](CNC(=O)O[C@H]2CC[C@H](C2)c2cc(NC(=O)Cc3cc(F)cc(F)c3)n[nH]2)C1

InChI Key InChIKey=OKGBWWNFKGXWTN-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 498751   

LigandPNGBDBM498751((1S,3R)-3-(3-{[(3,5- difluorophenyl)acetyl]amino}...)
Affinity DataKi:  1.99nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
Go to US Patent

LigandPNGBDBM498751((1S,3R)-3-(3-{[(3,5- difluorophenyl)acetyl]amino}...)
Affinity DataKi:  1.99nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
Go to US Patent