BDBM499201 US11014963, Example 100

SMILES COc1ccc(cc1)[C@H](NC(=O)C(Cc1cccc(Cl)c1)NC(=O)c1cccc(OCC(O)=O)n1)C(=O)N[C@@H](C(C)C)C(=O)C(F)(F)F

InChI Key InChIKey=BQSRTLXEDWLXNT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 499201   

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM499201(US11014963, Example 100)
Affinity DataIC50: 810nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent