BDBM499677 US11020398, Compound I-2::tert-butyl (cis-4-((5-(2-chlorobenzoyl)- 7H-pyrrolo[2,3-d]pyrimidin-4- yl)amino)cyclohexyl)carbamate

SMILES CC(C)(C)OC(=O)N[C@H]1CC[C@@H](Nc2ncnc3[nH]cc(C(=O)c4ccccc4Cl)c23)CC1

InChI Key InChIKey=LXZWTMZVXVHOCU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 499677   

TargetTyrosine-protein kinase BTK(Human)
Arqule

US Patent
LigandChemical structure of BindingDB Monomer ID 499677BDBM499677(tert-butyl (cis-4-((5-(2-chlorobenzoyl)- 7H-pyrrol...)
Affinity DataIC50: 17nMAssay Description:Full length unphosphorylated form of BTK expressed in Sf9 cells was employed to test inhibitory activity in the inactive BTK assay. The assay was mea...More data for this Ligand-Target Pair
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Date in BDB:
11/28/2021
Entry Details
US Patent