BDBM499694 2-cyclopropyl-6-(4-(6-(3-(dimethylamino)propoxy)-1'- methyl-6'-oxo-1',6'-dihydro-[3,4'-bipyridin]-3'-yl)-1H- pyrazol-1-yl)benzonitrile::US11020380, Example 382

SMILES CN(C)CCCOC1C=CC(c2cc(=O)n(C)cc2-c2cnn(-c3cccc(C4CC4)c3C#N)c2)=CN1

InChI Key InChIKey=NNYUYIJVUXHZTN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 499694   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 499694BDBM499694(US11020380, Example 382 | 2-cyclopropyl-6-(4-(6-(3...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent