BDBM499873 US11020398, Compound I-185::tert-butyl (trans-3-((5-(4- phenoxybenzoyl)-7H-pyrrolo[2,3- d]pyrimidin-4- yl)amino)cyclobutyl)carbamate

SMILES CC(C)(C)OC(=O)N[C@H]1C[C@@H](C1)Nc1ncnc2[nH]cc(C(=O)c3ccc(Oc4ccccc4)cc3)c12

InChI Key InChIKey=ZGAXWGCENPXDCW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 499873   

TargetTyrosine-protein kinase BTK(Human)
Arqule

US Patent
LigandPNGBDBM499873(tert-butyl (trans-3-((5-(4- phenoxybenzoyl)-7H-pyr...)
Affinity DataIC50: 57nMAssay Description:The active BTK assay consisted of phosphorylated form of full length BTK. The assay was performed in a buffer solution utilized in the inactive BTK a...More data for this Ligand-Target Pair
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Date in BDB:
11/28/2021
Entry Details
US Patent