BDBM50000081 CHEMBL358109::[2-(4-Chloro-phenyl)-ethyl]-methyl-(2-pyrrolidin-1-yl-ethyl)-amine

SMILES CN(CCN1CCCC1)CCc1ccc(Cl)cc1

InChI Key InChIKey=GHXKIAKUHUUOBY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50000081   

TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000081(CHEMBL358109 | [2-(4-Chloro-phenyl)-ethyl]-methyl-...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000081(CHEMBL358109 | [2-(4-Chloro-phenyl)-ethyl]-methyl-...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity was evaluated against sigma-1 binding site in guinea pig, using [3H]- -(+)- PentazocineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed