BDBM50000087 3-(2-Cyclopropylmethyl-octahydro-isoquinolin-4a-yl)-phenol::CHEMBL153538

SMILES Oc1cccc(c1)C12CCCC[C@H]1CN(CC1CC1)CC2

InChI Key InChIKey=KFIQKMINEHFZSM-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50000087   

TargetKappa-type opioid receptor(Guinea pig)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50000087(CHEMBL153538 | 3-(2-Cyclopropylmethyl-octahydro-is...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity to Opioid receptor kappa 1 in guinea pig cortex using [3H]EKC as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50000087(CHEMBL153538 | 3-(2-Cyclopropylmethyl-octahydro-is...)
Affinity DataKi:  4.20nMAssay Description:Binding affinity to Opioid receptor mu 1 in rat brain using [3H]-NAL as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000087(CHEMBL153538 | 3-(2-Cyclopropylmethyl-octahydro-is...)
Affinity DataIC50: 150nMAssay Description:In vitro inhibitory activity against opioid receptor in Guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2019
Entry Details Article
PubMed