BDBM50000439 5-Butyl-pyridine-2-carboxylic acid::5-Butyl-pyridine-2-carboxylic acid (fusaric acid)::CHEMBL24510
SMILES CCCCc1ccc(nc1)C(O)=O
InChI Key InChIKey=DGMPVYSXXIOGJY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50000439
Affinity DataKi: 149nMpH: 4.5Assay Description:Binding affinity towards Dopamine beta hydroxylase using tyramine substrate at pH 4.5 in the absence of fumarateMore data for this Ligand-Target Pair
Affinity DataKi: 149nMAssay Description:Compound was evaluated for the inhibition of Dopamine beta hydroxylase at pH 4.5More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of bovine adrenal medulla DBH incubated for 25 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of Dopamine beta hydroxylase in spontaneously hypertensive rats; Value ranges from 0.4-1.1More data for this Ligand-Target Pair
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 1.49E+5nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair