BDBM50000518 3-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyrylamino}-3-phenyl-propionylamino)-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-4-methylsulfanyl-butyrylamino)-succinamic acid::3-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyrylamino}-3-phenyl-propionylamino)-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-4-methylsulfanyl-butyrylamino)-succinamic acid (deltorphin A)::CHEMBL20775

SMILES CSCC[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(N)=O

InChI Key InChIKey=BHSURCCZOBVHJJ-NWOHMYAQSA-N

Data  8 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50000518   

TargetDelta-type opioid receptor(Rattus norvegicus (rat))
National Institute Of Environmental Health Sciences

Curated by ChEMBL
LigandPNGBDBM50000518(3-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-pro...)
Affinity DataKi:  0.120nMAssay Description:Binding affinity against Opioid receptor delta 1 in P2 membrane preparation of rat brain by [3H]DADLE displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
National Institute Of Environmental Health Sciences

Curated by ChEMBL
LigandPNGBDBM50000518(3-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-pro...)
Affinity DataKi:  0.450nMAssay Description:Compound was tested for its binding affinity against opioid receptor delta using [3H]-DPDPE as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
National Institute Of Environmental Health Sciences

Curated by ChEMBL
LigandPNGBDBM50000518(3-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-pro...)
Affinity DataKi:  2.13nMAssay Description:Inhibition of [3H]- ]DSLET binding to delta receptor from rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50000518(3-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-pro...)
Affinity DataKi:  143nMAssay Description:Inhibition of [3H]- ]DAMGO binding to mu receptor from rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
National Institute Of Environmental Health Sciences

Curated by ChEMBL
LigandPNGBDBM50000518(3-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-pro...)
Affinity DataKi:  290nMAssay Description:Inhibition of [3H]- ]DSLET binding to delta receptor from rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50000518(3-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-pro...)
Affinity DataKi:  336nMAssay Description:Binding affinity against Opioid receptor mu 1 in P2 membrane preparation of rat brain by [3H]DAGO displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50000518(3-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-pro...)
Affinity DataKi:  344nMAssay Description:Compound was tested for its binding affinity against opioid receptor mu using [3H]-DAGO as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50000518(3-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-pro...)
Affinity DataKi:  415nMAssay Description:Inhibition of [3H]- ]DAMGO binding to mu receptor from rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50000518(3-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-pro...)
Affinity DataIC50:  0.695nMAssay Description:Inhibition of [3H]- ]DSLET binding to opioid receptor delta from rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50000518(3-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-pro...)
Affinity DataIC50:  4.42E+3nMAssay Description:Inhibition of electrically evoked contractions in Guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50000518(3-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-pro...)
Affinity DataIC50:  281nMAssay Description:Inhibition of electrically evoked contractions in Guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50000518(3-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-pro...)
Affinity DataIC50:  98.3nMAssay Description:Inhibition of electrically evoked contractions in mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed