BDBM50001683 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::7-Benzyl-10-{[3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL294616::DPDPE
SMILES CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O
InChI Key InChIKey=MCMMCRYPQBNCPH-DVKRWUGUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 47 hits for monomerid = 50001683
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in mouse HN9.10 cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 610nMAssay Description:Displacement of [3H]DPDPE from rat mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 610nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cell membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Compound was evaluated for its inhibitory potency against opioid receptor delta of Mouse vas deferensMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Compound was evaluated for the binding affinity in comparison with [3H]-[p-Cl-Phe4]-DPDPE (opioid receptor delta selective ligand)More data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Compound was evaluated for its inhibitory potency against opioid receptor delta of Guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 609nMAssay Description:Compound was evaluated for its ability to displace [3H]- CTOP (opioid receptor mu selective ligand)More data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Inhibitory activity measured against Opioid receptor delta 1 using mouse vas deference assay (MVD).More data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibitory activity measured against Opioid receptor mu 1 using guinea pig ileum assay (GPI).More data for this Ligand-Target Pair
Affinity DataIC50: 619nMAssay Description:Inhibitory activity measured against [3H]CTOP (Opioid receptor mu 1) in rat brain using radioreceptor binding assays.More data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:Inhibitory activity measured against [3H]DPDPE (Opioid receptor delta 1 ligand) in rat brain using radioreceptor binding assays.More data for this Ligand-Target Pair
Affinity DataIC50: 385nMAssay Description:The ability to displace [3H]naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Ability to displace [3H]DPDPE from Opioid receptor delta 1 in rat brain membranes, was determined from radioreceptor assay.More data for this Ligand-Target Pair
Affinity DataIC50: 609nMAssay Description:Ability to displace [3H]CTOP from Opioid receptor mu 1 in rat brain membranes, was determined from radioreceptor assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Binding affinity towards Opioid receptor mu 1 was determined in guinea pig wholebrain using [3H]CTOP radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Binding affinity towards Opioid receptor delta 1 was determined in guinea pig wholebrain using [3H][4''-Cl-Phe4]-DPDPE as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibitory activity of the electrically induced guinea pig ileum longitudal muscle-myenteric plexusMore data for this Ligand-Target Pair
Affinity DataEC50: 7.30E+3nMAssay Description:Effective concentration was measured towards mu opioid receptor using guinea pig ileum (GPI,mu) bioassay in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 609nMAssay Description:Binding affinity opioid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Binding affinity opioid receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 4.10nMAssay Description:Effective concentration was measured towards delta opioid receptor using mouse vas deferens(MVD, delta) bioassay in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibitory potency against Opioid receptor mu 1 was determined in electrically induced strips of guinea pig ileum (GPI)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of binding of radioligand [3H][p-Cl-phe]-DPDPE to Opioid receptor delta 1 in rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibitory potency against Opioid receptor delta 1 was determined in electrically induced smooth muscle contractions of mouse vas deferens (MVD)More data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of binding of radioligand [3H]CTOP to Opioid receptor mu 1 in rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:Binding affinity towards mu opioid receptor was determined in rat brain using [3H]CTOP as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:Binding affinity towards delta opioid receptor was determined in rat brain using [H]-[p-Cl-Phe4]-DPDPE as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibitory concentration against electrically evoked contractions of guinea pig ileum longitudinal muscle-myenteric plexusMore data for this Ligand-Target Pair
Affinity DataEC50: 1.60nMAssay Description:Agonist activity at human delta opioid receptor expressed in mouse HN9.10 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 2.72E+3nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
Affinity DataEC50: 1.60nMAssay Description:Inhibition of [35S]GTP-gamma-S binding to human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 610nMAssay Description:Binding affinity towards Opioid receptor mu 1 using [3H]- CTOP as radioligandMore data for this Ligand-Target Pair
Affinity DataEC50: 7.30E+3nMAssay Description:In vitro bioassay data to determine the effective concentration required for antagonistic activity against Opioid receptor mu 1 in functional assay,G...More data for this Ligand-Target Pair
Affinity DataEC50: 4.10nMAssay Description:In vitro bioassay data to determine the effective concentration required for antagonistic activity against Opioid receptor delta 1 in functional assa...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Binding affinity towards Opioid receptor delta 1 using [3H]- [p-CIPhe4] DPDPE as radioligandMore data for this Ligand-Target Pair
Affinity DataEC50: 1.60nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 2.72E+3nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
Affinity DataEC50: 1.60nMAssay Description:Agonist activity at human delta opioid receptor expressed in mouse HN9.10 cell membrane by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Binding potency of compound in competition with [3H]DPDPE for Opioid receptor delta 1 tested in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:Inhibitory concentration against delta opioid receptor of electrically induced smooth muscle contraction of mouse vas deferensMore data for this Ligand-Target Pair
Affinity DataIC50: 570nMAssay Description:Inhibitory activity of the electrically induced smooth muscle contraction of mouse vas deferensMore data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:Evaluation for the binding affinity by competitive inhibition of [3H]- p-chloro DPDPE bindingMore data for this Ligand-Target Pair
Affinity DataIC50: >3.50E+4nMAssay Description:Evaluation for the binding affinity by competitive inhibition of [3H]- CTOP bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:Compound was evaluated for the binding affinity in comparison with [3H]- DPDPE (opioid receptor delta selective ligand)More data for this Ligand-Target Pair